Results of blastocyst cultures in Mini–incubators
- 43 % of the patients included in the study was over 40 years of age
- 62 % of the patients had 4 or more previous IVF/ICSI failures before this blastocyst culture
|
All transfers |
Blastocyst after 5 days of culture |
| No |
345 |
156 |
| Positive hCG |
170 |
87 |
| Pos hCG per transfer |
49,3% |
55,77% |
| Clinical pregnancy rate / ET |
31% |
38,46% |
Blastocyst culture is a very demanding process under which several things may improve the results if blastocyst is developed after 5 to 6 days.
The reasons for higher pregnancy rates per transfer is due to several factors:
- First of all the selection of the best embryos is improved and more transfers that could be performed at day 2 are cancelled.
- Second; the time between transfer and actual hatching and nihidation to the endometrium is shortened.
- Thirdly; 5 days after aspiration the natural contractions of the muscular wall of the uterus is reduced compared to the previous days.
- And finally the time to intervene for inflammatory processes after aspiration and between transfer and nihidation is reduced.
In conclusion it can be said, that if blastocysts are available for transfer at day 5 or 6 after aspiration, the chances of obtaining a pregnancy is imposing.